Game: Bond Breaker 2
Bond Breaker 2.0 places you in the world of the extremely small - where you need to manipulate protons, molecules, laser light, and more to solve challenging levels. Push and pull atoms around, combine them, split them, all while avoiding obstacles. Built as a collaboration between scientists at the CaSTL research c... Read more »
Game: Bond Breaker
Pit yourself against atomic physics in Bond Breaker, a puzzle game based on real nano-scale science. You start this game in the smallest way possible - as a single proton. You don’t even have an atom to call your own. Learn what it takes to be a proton, experience subatomic forces, and with luck and determination,... Read more »
Game: WolfQuest
Live the life of a wild wolf in Yellowstone National Park! You are a two-year old gray wolf born in the Northern Range of Yellowstone National Park. You learned the ways of the wolf in your birth pack. Now it's time for you to learn how to live on your own, finding food, meeting other wolves, and searching for ... Read more »
Game: Citizen Science
Citizen Science is an online flash-based computer adventure game in which the player is a young adult who becomes concerned about the health of a local lake threatened by eutrophication. Based at Lake Mendota in Madison, WI, the player's goal is to restore the lake. By focusing on the ecological needs of Lake Me... Read more »
Game: SORS
SORS is a medical simulation game with a sci-fi story. Players must diagnose patients using spatially offset raman spectroscopy by scanning them. The game mechanics are directly based on research papers for the SORS technique (which is being trialled in a UK hospital). Disease information, symptoms and treatments ar... Read more »
Game: ImmuneQuest
ImmuneQuest is an innovative educational game for college students that brings immunology to life. Designed to augment an educator’s existing curriculum, ImmuneQuest allows students to build and control a virtual immune system to defend their human host from increasingly cunning microbes. Immunology is complex, an... Read more »
Game: Voyager: Grand Tour
Voyager: Grand Tour is a physics puzzle game inspired by one of the most successful scientific missions in human history. For more than 35 years, the Voyager space probes have been on an incredible quest to explore the Solar System, uncovering amazing details about the outer planets and beyond. This game enables pla... Read more »
Game: Kerbal Space Program
KSP is a game where the players create and manage their own space program. Build spacecraft, fly them, and try to help the Kerbals to fulfill their ultimate mission of conquering space. The game is currently under heavy development. This means the game will be improved on a regular basis, so be sure to check back f... Read more »
Game: Meta!Blast
Prepare yourself... The last remaining plant cell in existence is dying. An expert team of plant scientists have inexplicably disappeared. Can you rescue the lost team, discover what is killing the plant, and save the world? Meta!Blast is a real-time 3D action-adventure game that puts you in the pilot's seat. S... Read more »
Game: Immune Defense
A two-dimensional strategy game in which various kinds of white blood cells can be bought and deployed in the war against 15 viral and bacterial pathogens. Players must use the right combination of cells for each combination of bacteria, viruses and parasites. Players also regulate the type of proteins that appear ... Read more »
Game: CellCraft
Exploring the cell through gaming. Build a cell, fight off viruses, survive harsh worlds, and save the Platypus species! This game was made possible by a grant from the Digital Media & Learning Competition. The goal was to make a truly educational game that was also genuinely fun to play. We hope students, tea... Read more »
Game: Plague, Inc.
I was very impressed how Plague Inc. makes a smooth, easy to play and still very complex and strategic game from reality. Similar to a board game, the action (and gore) is imagined but the game's mechanics are clear and gameplay is moving! You are a pathogen. You can choose to be a bacterium, virus or a pa... Read more »
Game: History of Biology
In the History of Biology game, you, the assistant, are required to navigate through a labyrinth of clues, objects, and internet sites trying to figure out why Dr. Shyre has disappeared. What secret project was he working on? Who might be after him and are they after you too? Hidden amongst the history of biology, D... Read more »
Game: Cell Defense: The Plasma Membrane
The only barrier between the cell and the dangers of the outside world is the plasma membrane. Defend your cell by building a functional plasma membrane and thwart the evil plans of Dr. Vial to destroy all life on earth! Learn how the membrane works and its parts, including phospholipids, cholesterol, proteins, and ... Read more »
Game: Cell Command
In Cell Command, students embark on a series of exciting missions aboard a microscopic "cell ship." At the outset, students operate a single station (e.g., the "ribosome station"), but eventually command all the ship's functions (e.g., duplication, membrane, mitochondria, golgi complex) simul... Read more »
Game: Biochem Gems
Biochem Gems is a deceptively simple-looking puzzle game that teaches players about the molecular building blocks of life. In this match-three gem-busting puzzler, players are asked to construct the biochemical compounds that compose everything from carbohydrates and fatty acids to nucleic and amino acids. Biochem ... Read more »
Game: Build-a-Cell
Overview Build-A-Cell is a drag and drop game to teach students about the organelles and organelle substructures within a plant, animal, bacterial, and fungal cell. How to play Build-a-Cell Drag the first organelle from the tray on the right side As each organelle is placed in the cell, the next one is unlocked ... Read more »
Game: Forgotten Island
Go Adventuring! Immerse yourself in the mysterious and puzzling world of Forgotten Island. Trapped in the middle of nowhere, you take on the role of a lost adventurer with a secret past. A mysterious explosion has destroyed the island's biology lab and scattered living specimens across the strange landscape. No... Read more »
Game: Crazy Plant Shop
In Crazy Plant Shop, students learn about genes and inheritance by breeding zany plants like the Chomplex (plants with big chompy teeth), Catcus (cactus cats), and Bunnyon (onion bunnies)! Special order requests from mysterious customers require students to understand dominant and recessive traits and how genetic tr... Read more »
Game: MedMyst
MedMyst (short for Medical Mysteries) is a Flash-based game that consists of six different missions in which the player has to solve a disease outbreak. Careers such as epidemiologists, microbiologists and veterinarian are explored. The six different missions can be played in any order. This description was provid... Read more »
Game: Pandemic II
Similar to a board game, action is imagined but clear and moving! This game is all about strategy! Various versions of the game are available for PC and Mac desktops/laptops. We are describing the web version here. You are a pathogen. You can choose to be a bacterium, virus or a parasite. Your goal is to kill ... Read more »
Game: Powers of Minus TEN-Cells and Genetics
Powers of Minus Ten lets you interactively zoom into a human hand and explore environments with scientifically-accurate 3D content. Discover some of the basic concepts in biology and learn about the structures of a few of the key cells, proteins, and molecules found in our bodies. POMT is... meant to be a general... Read more »
Game: Science Supremo: Clinical Trials
Science Supremo: Clinical Trials is a prototype game designed for the classroom that offers young people studying the new GCSE Science curriculum an opportunity to get a feel for what it means to be a scientist and to understand the interplay between science and society. Students take on the role of scientists work... Read more »
Game: Knowledge Mine beta
Linneaus or Darwin? Fungus or Plant? Translation or Transcription? Put your biology knowledge to the test in Knowledge Mine! Knowledge Mine is a biology trivia game intended for high school and post secondary students. Containing over 3,500 questions in such topics as biochemistry, human anatomy, genetics, ecology... Read more »
Game: Dragon Breeder Beta
Deep within the membrane of a giant egg, an ancient and dangerous creature lies dormant - a dragon! Learn about genetic inheritance as you breed dragon species, complete phenotype missions and meet monstrous creatures in a cloud-hopping sky world! Become the dragon master by breeding all types of dragons. Dragon ... Read more »
Game: Impulse
Impulse is an immersive, blended-genre physics game designed for the web and mobile devices. Combining elements of puzzle, arcade, educational, and simulation games, Impulse places players in an N-body simulation of ambient particles obeying Newton’s Laws. Impulse requires the player to apply a force (an impulse) th... Read more »
Game: Quantum Spectre
Use mirrors, lenses, and more to guide laser beams through mazes to reach colored targets in this scientifically accurate and wildly cool laser game. Watch out for the spectres… they will haunt you! Quantum Spectre is a puzzle-style game. Each level requires the player to direct one or more laser beams to targets w... Read more »
Game: EyeWire
EyeWire is an online community of “citizen neuroscientists” who map neural connections by playing a game. EyeWire is a game where you map the 3D structure of neurons. By playing EyeWire, you help map the retinal connectome and contribute to the neuroscience research conducted by Sebastian Seung's Computational ... Read more »
Game: EteRNA
The EteRNA game consists of puzzles, lab activities, player projects, strategy design, and community support. It crowdsources the computationally challenging tasks of RNA design and structure prediction. Puzzles consist of a target structure that players attempt to satisfy by the placement of different nucleotides. ... Read more »
Game: Code Fred: Survival Mode
He's not out of the woods yet. Incredible phenomena are happening in your body all the time. But have you ever stopped to think about what keeps you breathing, how information travels from your senses to your brain instantly, or any of the other amazing things that constantly happen to keep you alive? Now you c... Read more »
Game: CSI: The Experience
In CSI: The Experience, students learn what it takes to be a forensic scientist. The games are based on the popular CBS show CSI, but prior knowledge of the television series is not required. In Case One: Rookie Training, students learn the underlying science of different forensic disciplines such as forensic bio... Read more »
Game: You Make Me Sick!
In You Make Me Sick!, students take on the role of a pathogen and custom design their disease to infiltrate a variety of unique target hosts. As they progress, they must improve their infectious properties in order to infect hosts that have progressively stronger defenses (like antibiotics and stellar hygiene), ulti... Read more »
Game: Prisoner of Echo
In Prisoner of Echo, students learn about the properties of sound by attempting to escape an asteroid base that's been overrun by acoustical robots; blind robots that understand the world purely through sound. In Prisoner of Echo, students play a researcher trapped on the asteroid 60 Echo, in a facility patroll... Read more »
Game: Progenitor X
Progenitor X is a narrative-driven, turn-based, puzzle-solving game where the player will learn about the relationships between cells, tissues, and organs. This scientific concept is a core biology science standard taught from middle school to college. By employing turn-based puzzle mechanics, Progenitor X seeks to ... Read more »
Game: Immune Attack
Navigate a nanobot through a 3D environment of blood vessels and connective tissue in an attempt to save an ailing patient. Teach white blood cells how to hunt and kill bacterial invaders. Along the way, you will learn about the biological processes that enable macrophages and neutrophils to detect and fight infec... Read more »
Game: Cool Science Careers
In Cool Science Careers, students can experience what it's like to be a scientist. In Profession Pathfinder, students are matched to one of the careers on the website based on their answers to career interest questions. In Imagine Yourself, students can select five different career fields and virtually try out... Read more »
Game: Earth Primer
Earth Primer is a science book for playful people. Discover how Earth works through play—on your iPad. Join a guided tour of how Earth works, with the forces of nature at your fingertips. Visit volcanoes, glaciers, sand dunes. Play with them, look inside, and see how they work. Earth Primer defies existing genres, ... Read more »
Game: Agent Higgs
Agent Higgs is hiding from the prying eyes of physicists, and he needs your help! After playing through these addicting Particle Physics puzzles, you'll look at the Standard Model in a very non-standard way. But don't be scared -- no background knowledge is expected or required. You'll learn everythi... Read more »
Game: Possible Worlds
Possible Worlds digital games are designed to help improve student understanding of phenomena that are often the subject of scientific misconceptions. Developed by the Center for Children and Technology, the games are the centerpieces of modules that address four topics: photosynthesis, heredity, electricity, and he... Read more »
Game: Challenge and Persuade
Challenge and Persuade is a game of argument! In this game, players develop arguments and challenge each others’ ideas. A Judge decides the winning argument! The cards provide easy-to-read facts for any level player to construct an argument around topics at the nexus of energy, water, and climate. Challenge and Per... Read more »
Game: Thirst for Power
The Game of Strategy! Thirst for Power from Nexus Games is a strategy and resource management game in which players are governors of regions and compete to be the first to provide for their citizens' energy needs. The objective is to be the first player to meet the region's energy goal without exceeding it... Read more »
Game: Synmod
The game is aimed to teach the principles of synthetic biology. The goal of the game is to create novel antibiotics and kill several multidrug-resistant nasty bugs. The introduction to the game explains the development of drug resistance and a way to overcome it. The players will learn the principles of modularity ... Read more »
Game: Play to Cure: Genes in Space
NOTE: This application is designed for iPhone 4S and higher, along with iPad 2 and higher. You can play on older devices, but your gaming experience may not be the same. Beating cancer through a space game never seemed possible. Until now. Every day, scientists across the globe are painstakingly analyzing the gene... Read more »
Game: Happy Match
Are you a classifying genius? Are you a keen observer of all things nature? Then Happy Match is the game for you! In this twist on the on the classic quiz game, players participate in scientific research by classifying photos of animal, plant and insect species. There are different versions of Happy Match for all ... Read more »
Game: Fair Play
In Fair Play, players assume the role of Jamal, a young African American graduate student, on his journey to become a renowned professor. To succeed in the game, players must maintain a diverse academic social network while running a research lab. Over the course of the game, players will interact with a diversity o... Read more »
Game: Against the Gradient
A microscopic world is in need of your help. Take control of 16 cell membrane transporters to move molecules and ions into and out of cells. Over twenty unique puzzles will take you through the tough world of cell membrane transporters. Use channels, co-transporters, and antiporters to help the cell reach goal conce... Read more »
Game: SpaceChem
Zachtronics Industries is back with an ambitious new design-based puzzle game. Take on the role of a Reactor Engineer working for SpaceChem, the leading chemical synthesizer for frontier colonies. Construct elaborate factories to transform raw materials into valuable chemical products! Streamline your designs to mee... Read more »
Game: Universe Sandbox
Create and destroy on a scale you've never imagined with the ultimate space simulator. Harness the power to create black holes, collide galaxies, and manipulate gravity with just a few clicks. Inspired by the software astronomers use to unlock the mysteries of our universe, never before has astronomy been so in... Read more »
Game: Creative Connections, Picture Edition
In Creative Connections, Picture edition, players creatively combine representative pictures and then develop a fun fable from those connections. Nonreaders can create connections with common items. For 2-6 nonreaders of all ages. Combine this with the STEM edition so everyone in the family can join the fun! Desc... Read more »
Game: Creative Connections, STEM Edition
In Creative Connections, STEM edition, players form unique connections between common scientific, technical, engineering, and mathematical items and then develop a fun fable from those connections. Players gain points for combining two or more cards to create a new item. Description Provided by Developer Read more »
Game: Splice
Our latest game sees you creating life from nothingness—but to what end? Re-sequence, mutate, and splice your way through this unique puzzle experience. Splice is an experimental and artistic puzzler. Immerse yourself in its microbial world and start splicing! Every level ("strand") consists of a number ... Read more »
Game: Coaster Creator
Rapid energy transfer is the key to roller coaster thrills but be careful - too much kinetic energy and you'll crash, too little and you'll stall. Students use their knowledge of potential energy and kinetic energy to design their own coaster. Only the most skilled Coaster Creators make it onto the competiti... Read more »
Game: Profit Seed
Profit Seed lets you play as the wind in a game about genetically modified crops! The Profit Seed game explores the issues surrounding genetically modified organisms (GMO) and the patenting of agricultural seeds. It is also an experiment with a novel game mechanic. A player uses her mouse to control the wind, tryi... Read more »
Game: RePlay Health
A role-playing sport that allows 10 players to experiment with the U.S. health system–how it works and how can it be fixed! RePlay Health is a role-playing sport where players must balance performing physical activities to score points with trying to monitor and improve their character's health. The game takes ... Read more »
Game: ZOMBIEPOX
1-4 player game in which players fight the spread of zombies that threatens to take over the town. ZOMBIEPOX® has reached your town and turned two people into full-blown zombies! ZOMBIEPOX spreads as the zombies wander through town biting people! Help the humans escape the wrath of the flesh-eating zombies by vacc... Read more »
Game: POX: SAVE THE PEOPLE
POX: SAVE THE PEOPLE® is a new board game that challenges 1-4 players to stop the spread of a deadly disease. Not only is the game fun, but through play, players understand group immunity and the need to vaccinate. Many public health groups need to better promote immunizations in order to continue to prevent vaccin... Read more »
Game: Genomics Digital Lab
Genomics Digital Lab (GDL) is an award winning, integrated on-line learning environment where users experience the world of biology through immersive discovery-based learning. Unlike textbooks, GDL takes an integrated, hands-on approach to help learners understand the big picture of cell biology and its importance i... Read more »
Game: PurposeGames
PurposeGames is a web site for learning and having fun at the same time. Not possible? Think again. It all started while playing a famous trivia game with friends and family, realizing how little I knew about Geography. I wanted to get better at it, but could not achieve this by simply studying an Atlas. So I crea... Read more »
Game: Solve the Outbreak
New outbreaks happen every day and CDC’s disease detectives are on the front lines, working 24/7 to save lives and protect people. When a new outbreak happens, disease detectives are sent in to figure out how outbreaks are started, before they can spread. In this interactive, engaging app, you get to decide what t... Read more »
Game: Quarked! Adventures in the Subatomic Universe
Quarked! - Adventures in the Subatomic Universe brings subatomic physics to life through a multimedia project including an interactive website, a facilitated program for museums and schools, and an educational outreach program. Animated segments focus on the adventures of Ushi (up-quark), Danny (down-quark), and Har... Read more »
Game: Game Blocks
Game Blocks is a free, open source library for making games. A purely visual programming toolkit, it was built with BYOB (Build Your Own Blocks) from UC Berkeley, which is built on top of Scratch. Game Blocks was developed as a teaching aid by game developer Sheldon Pacotti for a course at the University of Texas ... Read more »
Game: Cell HD: emergence
The biochemistry of the human body is the subject of this action surgery game from New Life Interactive. A deep simulation, made from nearly a million "dynamic voxels," enables membranes, infections, germs, T-cells, antibodies, and some ill-meaning nanotechnology to come alive to a degree not possible wit... Read more »
Game: Snurfle Meiosis and Genetics
Snurfles, just like any other organism, must reproduce in order to continue as a species! But how does this happen? By the end of this game, you will understand how MEIOSIS and FERTILIZATION work to make offspring! You will also see how GENETIC characteristics are passed on through these processes and the connection... Read more »
Game: Healing Blade
Which are YOU? An Apothecary Healer or a Lord of Pestilence? Choose your destiny and determine the course of events in the groundbreaking new game from Nerdcore Learning and Wulven Game Studios. Developed by two physician/gamers, Healing Blade plunges the player into a world of sorcery and creatures, where real-wo... Read more »
Game: Reconstructors
Reconstructors is a game series in which students learn about the health effects of drugs of abuse and the underlying neuroscience. The series consists of three independent web adventures: Uncommon Scents: Students investigate a chemical accident and learn about the health effects of exposure to toxic chemicals. T... Read more »
Game: N-Squad
There are three episodes of N-Squad that reveal the answer to the question of whether a fatal car crash was the result of foul play or an accident. Each of the episodes contains games such as ADH Attack that describe the biological impacts of alcohol abuse. Episode 1: Digestive System Episode 2: Circulatory Syst... Read more »
Game: Phylomon
Phylomon is an online initiative aimed at creating a Pokemon card type resource but with real creatures on display. The intent is to boost knowledge and awareness of the many different species of animals and habitats present in the world. The game is played in a similar fashion to the popular card game. However, car... Read more »
Game: The Cure
The Cure is a serious, biology-based card game. Assemble the best hands and you can win - just like poker. The challenge with The Cure is that we don't know the rules yet! Until you play, we can't tell you if you have the equivalent of a royal flush or a pair of 2s. By playing the game, you will be both teac... Read more »
Game: Mobianga
Mobianga is essentially a matching game. Given a gene as a prompt, research journal articles and find the disease most closely linked to that gene. The most important part is that the game doesn't know if your answer is the correct one! Using previous answers on the same prompt, we compare your answer to others ... Read more »
Game: DNA Damage
Link nucleotides to repair DNA! Pair the correct nucleotides (gray) with the proper bases on the moving DNA strands. To move to the next level, connect as many of the proper pairs as possible. You will cause mutations if you make incorrect pairs or allow unpaired bases to escape off the right side of your screen! If... Read more »
Game: Dizeez
Dizeez is a multiple choice quiz where the player is presented with a disease (the “Clue”) and a multiple-choice selector with five genes, only one of which has prior evidence linking it to the Clue disease. We used a set of 3,439 candidate gene-disease links mined from the Gene Wiki as the input data set for the Di... Read more »
Game: Elementeo
Make science come to life while learning about elements and compounds. Elementeo Chemistry Card Game (V2) is a board game that adds excitement and intrigue to learning. Each element has a card containing its own personality, illustration and story. Also on the card are the element's symbol, atomic mass and numbe... Read more »
Game: Gamestar Mechanic
Gamestar Mechanic is a game-based platform and curriculum that teaches youth ages 8 – 14 how to design their own video games to foster systems thinking and 21st century skill building (problem solving, critical thinking, iterative design, creativity and collaboration), and to create a powerful motivation for STEM (s... Read more »
