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Deals with Biology // Body systems // Cell Biology // Chemistry // Disease // High School // Middle School // Molecular Science
  immune system, receptor/ligand interactions, proteins, cytokines, cell communication
Intended for 10+ // 10-13 // 13-16 // 16-18 // 16-19
Available on Microsoft Windows
Cost Free
Developed by FAS Learning Technologies Program (external)
Website at Visit game website (external)
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Immune Attack

Navigate a nanobot through a 3D environment of blood vessels and connective tissue in an attempt to save an ailing patient. Teach white blood cells how to hunt and kill bacterial invaders. Along the way, you will learn about the biological processes that enable macrophages and neutrophils to detect and fight infections.

Immune Attack is funded by the National Science Foundation and jointly developed by the Federation of American Scientists, the University of Southern California, Brown University, and Escape Hatch Entertainment. It teaches immunology in a fun and engaging way that is different from the traditional classroom setting, making use of the “challenge and reward” paradigm found in most video games.

Immune Attack is a supplemental teaching tool, designed to be used in addition to middle school and high school biology textbooks. Immune Attack introduces molecular biology and cellular biology in detail that is usually reserved for college students. However, it uses the familiar and motivational video game format to introduce the strange and new world of cells and molecules. Teachers are encouraged to refer to Immune Attack as an example of biological processes, and to give FAS feedback on how you have used Immune Attack in your classroom.

This game is free, works on Windows XP and all later versions, install the latest version of Microsoft DirectX before playing. Not available for MacOS.

This description was provided by the developer.

Video of Immune Attack

Screenshots of Immune Attack


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Player Reviews
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12.7 / 15
4.0 / 5
4.3 / 5
4.3 / 5

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Player Reviews

Reminds me of innerspace

September 13, 2012


Overall it was fun, point and shoot. I didn't get too far, but here's what I thought:

  • Add subtitles by default. I actually don't know if they exist but I didn't find an option after looking. I really emphasize this for those who are hard of hearing and for those who can't play with headphones.
  • The farthest I got (which wasn't terribly far I'm guessing) involved hunting down some green foreign invaders and leading the macrophage to gobble them. This quickly became more like a chore than actual fun because the invaders were so small. I like exploring every corner of my house when I'm dusting because I'm a clean freak. When I'm playing a game, I'm looking to escape that work. A radar for that section might have helped?
  • The beauty is in how you can select anything and learn about it. It makes you instantly curious about every thing that looks different. Why is that glowing? Why is that blue? That alone encourages learning extremely well.

Rating explanations: - Fun 4: If not for the chore like fashion of finding the green foreign bodies, this would be 5. - Learning 5: I definitely learned a lot and it's great because you are teaching, which means you have to learn. - Science 5: But I am assuming because I was learning. :D

Fun rating: 4.0 out of 5

Learning rating: 5.0 out of 5

Science rating: 5.0 out of 5


14.0 / 15

This review has 1 comment.

Immune Attack

September 12, 2012


I thought it was pretty good. Information packed. Great cut scenes. As far as the controls; being able to change mouse flight sensitivity. Graphics are good. Concept is great. At the beginning of the levels where they give information on the mission, a skip button wont hurt after the first time. Overall, pretty good.

Fun rating: 3.0 out of 5

Learning rating: 5.0 out of 5

Science rating: 5.0 out of 5


13.0 / 15

This review has 0 comments.

Immune Attack

September 12, 2012


Immune attack is a cool game. It is difficult until you learn how to play it.

Fun rating: 5.0 out of 5

Learning rating: 3.0 out of 5

Science rating: 3.0 out of 5


11.0 / 15

This review has 0 comments.

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