Immune Defense
Deals with biology // body systems // cells // disease
  phagocytes // antibodies // pathogens // bacteria // viruses // parasites // T-cells // B-cells // white blood cells // proteins
Intended for middle school // high school // university
Available on Web // Android // iOS // Windows // Mac
Cost free
Developed by Molecular Jig Games (external) (professional developer)
Website at Visit game website (external)
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Immune Defense

A two-dimensional real time strategy game in which the player commands the immune system at the molecular level.

The demo version of Immune Defense is available for "Pay what you want" at Immune Defense is designed based on our research with the game Immune Attack that showed lots of learning and gains of confidence. You can read more of our research at

Players learn practical molecular cell biology by using cells, signals and receptors as tools:

  • 3D shape matters
  • Bind to signals
  • Cause cellular behaviors when they bind
  • Cellular behaviors do not occur in presence of signal if receptor is absent
  • Receptors are proteins
  • Signals

  • Move randomly, cannot “find” the receptor
  • Only bind to receptors they match shapes with
  • Signals can be proteins
  • Cells

  • Cannot locate the bacterium unless signal and receptors function
  • Will move in the wrong direction if a signal binds a receptor on the wrong side
  • The wrong receptor will not work: if cell is missing a receptor, the cell is missing a function
  • Research on Immune Defense in on going. Would you like to help? Contact us at Molecular Jig Games.

    Video of Immune Defense

    Screenshots of Immune Defense

    Real Time Strategy getting hectic.  Three different kinds of bacteria are in the wound, how will you catch them all in time? Zoomed out, we can see a large area we are responsible for. Zoomed in, we can see the state of our cells.  Select cells to change their receptors, click on bacteria to see how to catch them. The database provides game play tips and neat, real life pictures. Play now!  Go to [Molecular Jig Games!](


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