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Deals with	physics
Intended for	middle school // high school
Available on	Web // Windows // Mac
Cost	free

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Deals with	chemistry // math // molecular science // physics
Intended for	middle school // high school // university
Available on	Android // iOS // Windows // Mac
Cost	paid

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Kerbal Space Program

Deals with	astrophysics // computer science // technology development
Intended for	high school // university
Available on	Windows // Mac
Cost	paid // free demo

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Gravity Simulator

Deals with	astrophysics // math // physics
Intended for	middle school // high school // university
Available on	Web // Windows // Mac
Cost	free demo

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Deals with	biology // cells // ecology // evolution // math
Intended for	elementary school // middle school // high school // university
Available on	Windows
Cost	paid

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Deals with	ecology // experimental design // technology development
Intended for	middle school // high school
Available on	Windows
Cost	paid

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The Electric Shocktopus

Deals with	physics
Intended for	elementary school // middle school // high school // university
Available on	Web // Windows // Mac
Cost	paid // free demo

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Deals with	biology // ecology
Intended for	middle school
Available on	Windows // Mac
Cost	paid // free demo

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Deals with	biology // medicine
Intended for	high school // university
Available on	Windows // Mac
Cost	free demo

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Deals with	biology // body systems // cells
Intended for	university
Available on	Windows // Mac
Cost	free

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